首页> 外文OA文献 >Management of Localized Prostate Cancer by Focal Transurethral Resection of Prostate Cancer: An Application of Radical TUR-PCa to Focal Therapy
【2h】

Management of Localized Prostate Cancer by Focal Transurethral Resection of Prostate Cancer: An Application of Radical TUR-PCa to Focal Therapy

机译:局灶性经尿道前列腺电切术治疗局限性前列腺癌:根治性TUR-PCa在局灶性治疗中的应用

代理获取
本网站仅为用户提供外文OA文献查询和代理获取服务,本网站没有原文。下单后我们将采用程序或人工为您竭诚获取高质量的原文,但由于OA文献来源多样且变更频繁,仍可能出现获取不到、文献不完整或与标题不符等情况,如果获取不到我们将提供退款服务。请知悉。

摘要

Background. We analyzed radical TUR-PCa against localized prostate cancer. Patients and Methods. Seventy-nine out of 209 patients with prostate cancer in one lobe were studied. Patients' age ranged from 58 to 91 years and preoperative PSA, 0.70 to 17.30 ng/mL. In other 16 additional patients we performed focal TUR-PCa. Patients' age ranged from 51 to 87 years and preoperative PSA, 1.51 to 25.74 ng/mL. Results. PSA failure in radical TUR-PCa was 5.1% during the mean follow-up period of 58.9 months. The actuarial biochemical non-recurrence rate was 98.2% for pT2a and 90.5% for pT2b. Bladder neck contracture occurred in 28 patients (35.4%). In 209 patients, pathological study revealed prostate cancer of the peripheral zone near the neurovascular bundle bilaterally in 25%, unilaterally in 39% and no cancer bilaterally in 35%, suggesting the possibility of focal TUR-PCa. Postoperative PSA of 16 patients treated by focal TUR-PCa was stable between 0.007 and 0.406 ng/mL at 24.2 months' follow-up. No patients suffered from urinary incontinence. Bladder neck contracture developed in only 1 patient and all 5 patients underwent nerve-preserving TUR-PCa did not show erectile dysfunction. Conclusion. Focal TUR-PCa was considered to be a promising option among focal therapies against localized prostate cancer.
机译:背景。我们分析了针对局部前列腺癌的根治性TUR-PCa。患者和方法。在一个叶中研究了209名前列腺癌患者中的79名。患者年龄为58至91岁,术前PSA为0.70至17.30ng / mL。在其他16名患者中,我们进行了局灶性TUR-PCa。患者年龄为51至87岁,术前PSA为1.51至25.74ng / mL。结果。在58.9个月的平均随访期间,根治性TUR-PCa的PSA失败率为5.1%。 pT2a的精算生化非复发率为98.2%,pT2b的为90.5%。膀胱颈部挛缩发生在28例患者中(35.4%)。在209例患者中,病理研究表明,双侧神经血管束附近的周围区域的前列腺癌占25%,单侧占39%,而双侧无癌占35%,提示可能存在局灶性TUR-PCa。在24.2个月的随访中,接受局灶性TUR-PCa治疗的16例患者的术后PSA稳定在0.007至0.406μng/ mL之间。没有患者患有尿失禁。仅1例患者出现膀胱颈挛缩,所有5例接受神经保护的TUR-PCa均未显示勃起功能障碍。结论。局灶性TUR-PCa被认为是针对局部前列腺癌的局灶性治疗方法中的一种有前途的选择。

著录项

  • 作者单位
  • 年度 2012
  • 总页数
  • 原文格式 PDF
  • 正文语种 {"code":"en","name":"English","id":9}
  • 中图分类

相似文献

  • 外文文献
  • 中文文献
  • 专利
代理获取

客服邮箱:kefu@zhangqiaokeyan.com

京公网安备:11010802029741号 ICP备案号:京ICP备15016152号-6 六维联合信息科技 (北京) 有限公司©版权所有
  • 客服微信

  • 服务号